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     asthma





 
 General information  Diagnosis
 What happens to lungs  Treatment
 Factors that trigger asthma World asthma day
 Common allergens Valuable information
 Anatomy FAQs
 
General Introduction

Asthma is one of the most common chronic diseases in the world. Perhaps the most commonly discussed respiratory disease after the common cold. The word asthma is derived from a Greek work meaning 'breathlessness or panting" both of which accurately describe an attack of asthma.

"Among the Diseases whereby the Region of the breath is wont to be infested, if you regard their tyranny and cruelty, an Asthma (which is sometimes by reason of a peculiar symptom denominated likewise an Orthopnoea) doth not deserve the last place; for there is scarce any thing more sharp and terrible than the fits there of Breathing, whereby we chiefly live, is very much hindered by the assault of this disease, and is in danger, or runs the risk of being quite taken away."

-Thomas Willis, 1674 

An asthma attack leads to lung infection, tiredness and cough and it is not surprising that asthma is a leading medical cause of absenteeism of children from school and adults from work The attack can be seasonal when the pollen count is high in the atmosphere. An attack of asthma leads to breathing difficulties and the attack can be acute when it lasts for a short period or chronic when it lasts for days. The attack can also be mild or severe and a life threatening one.

An asthma attack leads to lung infection, tiredness and cough and it is not surprising that asthma is a leading medical cause of absenteeism of children from school and adults from work The attack can be seasonal when the pollen count is high in the atmosphere. An attack of asthma leads to breathing difficulties and the attack can be acute when it lasts for a short period or chronic when it lasts for days. The attack can also be mild or severe and a life threatening one.

The conservative estimates are that about 300 million people are suffering from the condition worldwide. In India, there are approx. 40 million who have the disease and the number is rising everyday. In recent decade there has been a global increase in the burden of the disease among both children and adults. This maybe due to westernization of lifestyles and increasing atmospheric pollution. By 2025.there are likely to be 400 million asthma sufferers worldwide. The more worrying aspect of the disease is that it accounts for about 1 in every 250 deaths worldwide and 90% of these deaths are preventable. Most deaths are due to delay in seeking help and sub-optimal long-term treatment strategies due to the lack of education and awareness about the disease.

What happens to lungs

Asthma is a condition in which the airways of the lungs become either narrowed or completely blocked, obstructing normal breathing. This obstruction of the lungs, however, is reversible, either spontaneously or with medication. That is why asthma is technically called Reversible Obstructive Airway Disease (ROAD). The basic abnormality causing asthma is the hyper responsive reaction of the body to specific and non-specific stimuli.

Air reaches the lung through the windpipe (trachea), which divides into two large tubes (bronchi), one for each lung. Each bronchi further divides into many little tubes (bronchioles), which eventually lead to tiny air sacs (alveoli), in which oxygen from the air is transferred to the bloodstream, and carbon dioxide from the bloodstream is transferred to the air.

Although the airways normally have the potential for constricting in response to allergens or irritants, the asthmatics airways are more prone to constriction due to increased response to allergens. This insult makes the airways more prone to infection leading to inflammation and swelling causing further constriction of the pipes. Infection also causes increased mucus production and this clogs the narrowed airways.

Once the airways have become obstructed, it takes more effort to force air through them and breathing becomes labored. This forcing of air through constricted airways can make a whistling sound, called wheezing. Irritation of the airways by excessive mucus may also provoke coughing.

Because exhaling through the obstructed airways is difficult, too much stale air remains in the lungs after each breath. This decreases the amount of fresh air which can be taken in with each new breath, so not only is there less oxygen available for the whole body, but more importantly, the high concentration of carbon dioxide in the lungs causes the blood supply to become acidic. This acidity in the blood may rise to toxic levels if the asthma remains untreated.

Factors that trigger asthma

Asthma episodes can be triggered by a variety of factors, most notably: allergens, Infections, environmental pollutants or non-specific stimuli such as exercise and emotional states.

Between 50 and 70 per cent of adults with asthma suffer from allergies. In children under three years of age, viral infections are likely to be the most common trigger. After three years, allergies also begin to play an increasing role as a trigger.

After 20 years of age, occupational exposure to toxic substances and allergens also can be important triggers for asthma.

Common allergens
Common allergens associated with asthmatic responses are :

Foods : Nuts, peanuts, chocolate, eggs, citrus fruits, milk

Plants or plant products : Pollens, grasses, mold spores

Animal or insect materials : Dust mites, animal dangers, feathers, canine or feline saliva Numerous scientific studies have shown that avoidance of specific allergens in patients with asthma who have been previously sensitized will result in improved asthma symptoms and decreased medication requirements

Anatomy
When the respiratory system is working properly, the air we breathe passes in and out of the lungs through a network of airways. But for people with asthma, even a minor irritant will set off an immune response that can shut down the airways.

Asthmatic symptoms are usually quite variable, someone with asthma may go for periods of time without symptoms, and then suddenly have severe episodes for days at a time. The most common symptom is wheezing.

Diagnosis

Blood analysis may show increase in the number of eosinophils (Eosinophil is a specific type of white blood cell that increases in allergic reactions).

Sputum examination may show increased eosinophils

The level of a certain antibodies can be elevated.

Chest X ray may show abnormality in the airway.

Arterial blood gas analysis shows decreased oxygen concentration in blood.

Pulmonary function tests (lung function tests) are helpful in judging severity of airway obstruction. To do this test a spirometer is used and the test is often called spirometery . A spirometer is an instrument that measures the maximum volume one can exhale after breathing in as much as one can .There are various values that are calculated and the interpretation of the test is done looking at a combination of values. Some of the common values looked at are as follows:

Forced Vital Capacity: or FVC: This is the total volume of air one can exhale after breathing in as much as one can,
Forced Expiratory Volume in One Second, or FEV1: This measures the volume of air one can exhale in the first second. In general, the more air you breath out during the first second of a full exhalation, the better.

Treatment
How can Asthma be treated ?

Remember asthma cannot be completely cured but can be prevented. Treatment of asthma can be divided into two broad categories:

Treatment of Acute attacks of asthma using quick-relief
medications.
Long Term treatment strategies

Treating an Acute attack of asthma -
The quick-relief medications work by relaxing bronchial smooth muscle and are called broncho-dilators. These can reverse an acute attack in a short time.

During an acute attack of Asthma the following should be done:

Always keep your blue inhaler with you.

Take a puff from the inhaler

Loosen any tight clothing and sit-up.

Open the windows of the room if room is warm and humid.

If no immediate improvement felt during an attack, continue to take one puff of inhaler every minute for 3 to 5 minutes or until symptoms improve.

If your symptoms do not improve in five minutes or if you are in doubt, call your doctor or visit the nearest hospital

It is important to recognize a life threatening attacks of asthma. This situation should be suspected if -

The reliever (blue) inhaler does not help.
The symptoms get worse (cough, breathless, wheeze, tight chest).
If you are too breathless to even speak

Long-term treatment strategies:
There are three broad strategies to follow:

Controlling the environmental factors 
Controlling asthma attacks by taking regular medications 
Monitoring Lung Function regularly

Controlling the environmental impact on asthma
The first step in long-term asthma management is trying to control the environment in which you live. Although the environment cannot be changed totally but one can control its impact on our health. 

The following measures would lessen asthma attacks

Wash the bedding used weekly in hot water (included sheets, pillow cases and mattress pads) 
Use dust-proof covers for mattress and pillows. 
Avoid pets with fur or feathers inside the house 
Avoid using bedding made of foam rubber with synthetic materials 
If house is carpeted consider replacing it with hardwood floors or tile 
Use air-conditioners for rooms 
The humidity of the house should be kept low 
World asthma day
World Asthma Day is observed on the first Tuesday in May. This year it falls on May 3. World Asthma Day is a organized by Global Initiative for Asthma (GINA) in association with World Health Organization and US National Heart, Lung and Blood Institute. The theme for 2005 is 'Unmet Needs of Asthma'. The primary goal of this day is to improve awareness about the disease among health care providers and workers,government officials , general public and all those under the grip of this disease.
Valuable information
More Valuable information about Asthma

Traditional Medicine for cure of Asthma :
Treatment to 'cure asthma' has been made by many alternative practitioners of medicine. How far these claims can be substantiated is unknown. Most doctors are a bit weary about these tall claims. 'Fish medicine' is one such claim. Similar claims are made by Chinese and Buddhist system of medicine. Normally one can try these medicines if they wish, however without stopping the inhalers and nebulizer as prescribed by the doctors. More integrated research is required between traditional and allopathic medicine before any conclusions can be safely made.

Fears that inhalers are addictive and are unsafe for use, are totally unfounded. In fact, with the use of inhalers and nebulizers; the treatment of asthma has been revolutionized and it is now much easier to treat asthma patients.

FAQs
Which specialist should I consult if I have Asthma ?
You should consult a General Physician or Respiratory Care Physician who also are called Pulmonologists.

Is there a cure for asthma ?
Asthma can be controlled effectively by medicines especially inhalers. These are safe to use and have minimum side effects, if any. Asthma cannot be eradicated from its roots as this is more of a hypersensitivity response of the body to certain allergens. One should accept the disease and learn to prevent an acute attack.

Does it run in the family ?
Yes, there are documented cases where heredity also is one of the factors causing asthma.

Will I get it if I get repeated attacks of cold ?
Contrary to popular belief, asthma has nothing to do with common cold. Asthmatic attacks can occur in spring when the pollen count is high. High pollen count can also cause sneezing and running nose.

Will traditional medicine cure me of asthma ?
Traditional medicine has always been used to treat asthma and fish medicine is one such medicine. Its effect is still being studied. There are no scientific studies to prove the claim made by the practitioners.

Will I get asthma if I am allergic to dust ?
Maybe. This is one of the predisposing causes for asthma.

Is it true that inhalers should not be used by asthmatics because they are addictive ?
Inhalers are very important in the treatment of asthma. They are not addictive.

Glossary
Eosinophils : Increase in eosinophils.

Allergen : A substance that can trigger an allergic reaction. Asthma can be triggered by dust mites, animal dander, mold, and cockroaches.

Alveoli : The small units of lungs, these are tiny air sacs where oxygen is transferred into lungs and carbon dioxide waste enters the airways in order to be exhaled out.

Bronchodilators : Drugs that relax the muscles around the airways and help in opening up the airways

Metered Dose Inhaler : The most common device people use to take asthma medication. An MDI allows you to inhale a specific amount of medicine (a "metered dose"). It consists of a metal canister, which keeps the medication under pressure, and a plastic sleeve, which helps to release the medication. When you press the canister, medicine particles are propelled toward your throat where you can inhale them.

Peak flow : A simple measurement of how well you can blow air out of your lungs. Peak flow meter is a small and inexpensive home device used to measure the peak flow.

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